The Tigers hung tough until around the 3-minute mark, when the Hogs extended their lead to double digits and never looked back.
Johnny O'Bryant led the way for the Tigers with 20 points and 16 rebounds, seven on the offensive glass. Andre Stringer chipped in 13 points off the bench, but no other Tiger scored in double figures.
Four of Arkansas' five starters scored at least 13 points, with Rashad Madden pacing the home-standing Razorbacks with 21 points, including a 12-of-14 effort from the charity stripe.
LSU returns to the PMAC for a Wednesday night game with Mississippi State.